Rishi Sunak is promising to create up to 20,000 more apprenticeships with a series of reforms including fully funding training for young people and cutting red tape for small businesses.
The government will pay the full cost of apprenticeships for people aged 21 or under at small firms from 1 April.
To enable this, it is pledging £60m of new investment for next year.
Labour said after 14 years of Tory "economic failure", small firms were finding things "harder and harder".
In a speech to a conference for small businesses in Warwickshire, the prime minister will set out a package of reforms he says will "unlock a tidal wave of opportunity".
As well as funding the cost of apprenticeships, ministers will also raise the amount of funding companies who are paying the apprenticeship levy can pass on to other businesses.
The levy, which was introduced in 2017, is paid by large firms with the aim of creating more apprenticeship places.
But business groups have called for reforms to the levy, with millions of pounds said to be going unspent each year.
From 6 April, businesses will be able to share up to 50% of unspent funds, up from the 25% they are currently able to transfer to another employer.
Between the changes to the levy and the investment in training, the government expects to enable up to 20,000 more apprenticeships.
Mr Sunak said the government was "sticking to the plan and leaving no stone unturned to make the UK the best place to do business".
