Researchers have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by motor neurone disease (MND).
The research was carried out by scientists at The Francis Crick Institute and University College London (UCL) including a Medical Research Council (MRC) Senior Clinical Fellow.
MND, also known as amyotrophic lateral sclerosis (ALS), is a rapidly progressing and devastating condition that causes paralysis by affecting motor neurons, with limited treatment options.
Until now, scientists were aware that a few proteins, especially a protein called TDP-43, were found in unexpected locations in ALS nerve cells.
