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A challenge-led approach will focus on distinct, disruptive or interdisciplinary activity with the potential to achieve success within 10 to 15 years.

Investments will be outward facing, fostering collaborative research and providing a stimulating environment to train the next generation of researchers and technologists.

The new model is a change to how the Medical Research Council (MRC) funds, which makes no judgement on the importance of any area of science.

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