Teachers from the National Education Union (NEU) have rejected what leaders have described as an 'insulting' pay offer, and will now stage further strikes in England this spring.
According to the union, 98% of members who took part in the ballot turned down the deal.
They said Education Secretary Gillian Keegan's latest pay offer "did not cut the mustard" and are now warning strike action could carry on into the autumn months.
Both Ms Keegan and Rishi Sunak branded the result "extremely disappointing", with Mr Sunak saying further strikes will be "enormously damaging" to children's education.
After a period of talks, teachers had been offered a one-off payment of £1,000 for the current school year and a 4.3% pay rise for most staff next year (2023/24).
But according to the NEU, the deal represents another two years of real-terms pay cuts and teachers in England would see their pay fall further behind their counterparts in Wales and Scotland.